The final scientific workshop for stakeholders, entitled “European Workshop on the Clinical Implementation of Dosimetry for Molecular Radiotherapy”, took place at the National Physics Laboratory (NPL) in Teddington, United Kingdom, on 20-21 May 2019.
The workshop presented the final results of this project. New protocols for comparison of quantitative imaging and commissioning of a Molecular Radiotherapy (MRT) dose calculation platform were presented in the context of multi-centre comparison exercises performed within the project. The outputs from the project put into context with presentations covering activity measurement, quantitative imaging and dosimetry in a clinical environment, in support of clinical trials and from a commercial prospective. The latest guidance on dosimetry and quantitative imaging for MRT from the EANM, MIRD and ICRP were presented for discussion.
The workshop agenda and details are available here.
Presentations for download (download all):
MRTDosimetry: a pan-European project establishing metrology for clinical implementation of dosimetry in molecular radiotherapy
Andrew Robinson, National Physical Laboratory, United Kingdom
New Activity Transfer Instrument: Can we improve the measurement of high-energy pure β-emitters in the hospitals?
Kelley Ferreira, National Physical Laboratory, United Kingdom
Clinical use of the secondary standard ion chamber
Steve Jeans, The Christie NHS Foundation Trust, United Kingdom
Activity calibration for clinical trials: alpha pharmaceuticals
Erlend Eikeland Myrnes, Bayer AS, Norway
Calibration and verification of quantitative imaging using SPECT/CT
Johannes Tran-Gia and Michael Lassmann, University of Würzburg, Germany
Monte Carlo Simulation of SPECT Imaging
Gunjan Kayal, SCK.CEN, Belgium and INSERM, France
Towards a vendor-independent standard for absolute quantitative SPECT/CT
Steffie Peters, Radboud university medical center, The Netherlands
Imaging and dosimetry for Ho-166
Gerrit van de Maat, Quirem Medical, The Netherlands
Commissioning of a dosimetry platform for MRT
Jill Tipping and Nick Calvert, The Christie NHS Foundation Trust, United Kingdom
NTCP uncertainties
Maurice Cox, National Physical Laboratory, United Kingdom
EANM Dosimetry guidelines: Compliance to individual treatment planning in Molecular RadioTherapy
Mark Konijnenberg, Erasmus MC, Rotterdam, The Netherlands
Metrology for clinical implementation of dosimetry in molecular radiotherapy MIRD
Robert Hobbs, Johns Hopkins Medicine Department of Radiation Oncology, USA
ICRP Publication 140: Radiological protection in therapy with radiopharmaceuticals
Glenn Flux, The Royal Marsden Hospital & Institute of Cancer Research, United Kingdom
Database of reference images and DICOM conversion tool
Andrew Robinson, National Physical Laboratory, United Kingdom
Final comments from a medical perspective
Markus Luster, University of Marburg, Germany